Journey of a Chemotherapy Drug through the Tumor Microenvironment
by Jeya Chelliah B.Vsc Ph.D. The tumor microenvironment (TME) is a complex and dynamic landscape, comprising not just the cancer cells themselves, but also a myriad of other cell types, extracellular matrix components, and signaling molecules. This intricate network plays a pivotal role
Potential Candidates and Research Areas for the 2023 Nobel Prize in Physiology or Medicine
by Jeya Chelliah B.Vsc Ph.D As the scientific community eagerly anticipates the announcement of the Nobel Prize in Physiology or Medicine on October 2nd, 2023, speculation is rife about who the potential winners could be and what areas of research might be highlighted.
How Embryonic and Tumor Microenvironments Master the Art of Immune Evasion
Jeya Chelliah B.Vsc Ph.D. The field of cancer research has long been fascinated by the uncanny similarities between embryonic microenvironments and tumor microenvironments (TMEs). Both settings exhibit a unique ability to evade the immune system, a phenomenon that has puzzled and intrigued scientists
Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors
Research Proposal: Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors Jeya Chelliah B.Vsc Ph.D. Chimeric Antigen Receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematological malignancies, achieving remarkable success in patients with acute lymphoblastic leukemia (ALL) and
Unraveling the Complexity: Why Neoantigens Pose Challenges for Cancer Immunotherapy
by Jeya Chelliah B.Vsc Ph.D. Today, we embark on a journey into the intricate world of cancer immunotherapy, specifically focusing on a topic that has stirred both curiosity and skepticism: neoantigens. Neoantigens, the altered protein fragments unique to cancer cells, have garnered attention
Mechanism of action of Leqvio® (inclisiran)
Now he owes the feds $375K
The dangers of using large language models for peer review
The dangers of using large language models for peer review The recent advances in artificial intelligence, and particularly large language models (LLM) such as chatGPT (openAI, San Francisco, CA, USA), has initiated extensive discussions in the scientific community regarding their potential uses and, more importantly,
NIH rules are supposed to stop ‘pass the harasser.’
New York hedge fund billionaire and an unnamed partner will spend $25 million relaunching research of embattled scientist
How to wrap up research projects gracefully
Four researchers offer tips on ending, redefining and handing over projects. Some research projects arrive gracefully at a natural conclusion, such as when a trainee leaves the laboratory. Others come to a screeching halt when funding runs out. Still more dance along the
Everyone Wants Your Email Address. Think Twice Before Sharing It.
Your email address has become a digital bread crumb for companies to link your activity across sites.
