Molecular Hallmarks of Cancer

Molecular Hallmarks of Cancer is a detailed exploration of the cellular and molecular foundations of cancer biology. This publication covers:

• The multi-step process of carcinogenesis and tumour progression

• Roles of oncogenes (e.g., KRAS, MYC) and tumour suppressor genes (e.g., TP53, RB1)

• Mechanisms of genetic and epigenetic regulation, including DNA methylation and chromatin modification

• The “cancer box” model that links growth-promoting and growth-suppressing gene networks

• Mechanisms of DNA damage and repair pathways (NER, BER, HR, and NHEJ)

• The molecular logic behind personalized cancer medicine

Illustrated with figures and examples, it is a valuable reference for oncologists, pathologists, biomedical researchers, and students in molecular biology.