The Nobel Prizes: A Tradition of Excellence

by  Jeya Chelliah BVSc Ph.D. Every year, the world turns its attention to the Nobel Prizes, a set of six prestigious awards that recognize outstanding contributions in various fields. These prizes are awarded for achievements in physiology or medicine, physics, chemistry, economic science,

Contagious Cancers: A Rare Phenomenon with Implications for Human Oncology

by Jeya Chelliah B.Vsc Ph.D. Cancer, a word that evokes fear and concern, is typically associated with individual affliction. However, nature has its own peculiarities. In certain species, cancer is not just an individual’s battle but can spread contagiously from one individual to

The three most recent papers on Cancer immunotherapy

Chest and thorax: Symptoms and toxicities Publication Year: 2024 Authors: Julie R. Bloom, Robert M. Samstein Abstract: In the last several decades, cancer-related treatment has significantly advanced including increased utilization of immunotherapy, improvement in surgical precision and radiation techniques, palliative medicine, emphasis on

Journey of a Chemotherapy Drug through the Tumor Microenvironment

by Jeya Chelliah B.Vsc  Ph.D The tumor microenvironment (TME) is a complex and dynamic landscape, comprising not just the cancer cells themselves, but also a myriad of other cell types, extracellular matrix components, and signaling molecules. This intricate network plays a pivotal role

Journey of a Chemotherapy Drug through the Tumor Microenvironment

by Jeya Chelliah B.Vsc Ph.D. The tumor microenvironment (TME) is a complex and dynamic landscape, comprising not just the cancer cells themselves, but also a myriad of other cell types, extracellular matrix components, and signaling molecules. This intricate network plays a pivotal role

Potential Candidates and Research Areas for the 2023 Nobel Prize in Physiology or Medicine

by Jeya Chelliah B.Vsc Ph.D As the scientific community eagerly anticipates the announcement of the Nobel Prize in Physiology or Medicine on October 2nd, 2023, speculation is rife about who the potential winners could be and what areas of research might be highlighted.

How Embryonic and Tumor Microenvironments Master the Art of Immune Evasion

Jeya Chelliah B.Vsc Ph.D. The field of cancer research has long been fascinated by the uncanny similarities between embryonic microenvironments and tumor microenvironments (TMEs). Both settings exhibit a unique ability to evade the immune system, a phenomenon that has puzzled and intrigued scientists

Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors

Research Proposal: Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors Jeya Chelliah B.Vsc Ph.D. Chimeric Antigen Receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematological malignancies, achieving remarkable success in patients with acute lymphoblastic leukemia (ALL) and

Unraveling the Complexity: Why Neoantigens Pose Challenges for Cancer Immunotherapy

by Jeya Chelliah B.Vsc Ph.D. Today, we embark on a journey into the intricate world of cancer immunotherapy, specifically focusing on a topic that has stirred both curiosity and skepticism: neoantigens. Neoantigens, the altered protein fragments unique to cancer cells, have garnered attention