A Novel Lens to Understand Immune Memory and Its Implications for Vaccine Development and Autoimmunity
Jeya Chelliah B.Vsc Ph.D. The persistence and specificity of immune memory are fundamental to the adaptive immune system’s ability to combat recurrent infections and form the basis of effective vaccination. However, despite substantial advancements, the exact molecular and cellular mechanisms by which immune
The Lock and Key Model vs. Quantum Tunneling in Enzyme Function
Jeya Chelliah B.Vsc Ph.D Quantum biology is an emerging field of science that explores the ways in which quantum mechanics—principles traditionally associated with non-living, microscopic particles like photons and electrons—impact biological processes that occur in living organisms. This field suggests that some biological
Unmasking DNA Polymerase Pausing in PCR: A Silent Disruptor
Jeya Chelliah B.Vsc Ph.D Polymerase Chain Reaction (PCR) is a cornerstone technique in molecular biology, renowned for its efficiency in amplifying specific DNA sequences. However, one rare yet insidious issue that can compromise PCR results is DNA polymerase pausing. This phenomenon, often
DNA Pausing as a Diagnostic Tool for Cancer: Potential and Challenges
Jeya Chelliah B.Vsc Ph.D Cancer diagnosis traditionally relies on imaging techniques, biopsy, and molecular markers. With advances in molecular biology, researchers are exploring innovative methods to detect early signs of cancer. One such area of interest is the detection of DNA pausing. Given
Understanding DNA Pausing: Mechanism, Occurrence, and Implications
Jeya Chelliahh B.Vsc Ph.D DNA pausing refers to a temporary halt in the process of DNA replication or transcription. During DNA replication, the machinery responsible for copying the DNA sequence pauses, leading to a temporary stop in the elongation of the new DNA
Novel In Vivo Imaging Techniques to Explore Microbiome-Immune System Interactions
Jeya Chelliah B.Vsc Ph.D. Recent advancements in microbiome research have underscored the profound impact of microbial communities on host physiology, particularly through their interactions with the immune system. To explore these interactions in unprecedented detail, we propose a novel experimental approach utilizing advanced
Strategies for Promoting Diversity and Inclusion in Research Labs
Jeya Chelliah B.Vsc Ph.D. In the competitive world of scientific research, fostering a positive and productive environment is essential for driving innovation and achieving excellence. Promoting diversity and inclusion within research labs is critical not only for ethical reasons but also for maximizing
Innovative Experimental Approaches to Unravel Cancer Immune Escape Mechanisms
Jeya Chelliah B.Vsc Ph.D. Understanding how cancer cells evade the immune system is crucial for improving immunotherapies and achieving better clinical outcomes. Here are some innovative experimental approaches to study the mechanisms of cancer immune escape: Single-Cell RNA Sequencing (scRNA-seq) Approach: Use single-cell
Unleashing Innovation: How ChatGPT Enhances Brainstorming in Life Science Research
Jeya Chelliah B.Vsc Ph.D. In the dynamic field of life sciences, innovation and fresh perspectives are crucial for groundbreaking discoveries. Traditional brainstorming sessions play a key role in generating research questions, fostering critical thinking, and exploring new experimental approaches. Now, with the advent
Starting Your First Lab: A Comprehensive Guide for New Investigators
Jeya Chelliah B.Vsc Ph.D. Embarking on the journey of establishing your own lab is an exhilarating milestone in any scientist’s career. After receiving your first grant, the next pivotal step is to set up a lab that will be the hub of your
