Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors
Research Proposal: Development of Dual-Targeting CAR-T Cells for Enhanced Specificity and Efficacy in Solid Tumors Jeya Chelliah B.Vsc Ph.D. Chimeric Antigen Receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematological malignancies, achieving remarkable success in patients with acute lymphoblastic leukemia (ALL) and
Unraveling the Complexity: Why Neoantigens Pose Challenges for Cancer Immunotherapy
by Jeya Chelliah B.Vsc Ph.D. Today, we embark on a journey into the intricate world of cancer immunotherapy, specifically focusing on a topic that has stirred both curiosity and skepticism: neoantigens. Neoantigens, the altered protein fragments unique to cancer cells, have garnered attention
Mechanism of action of Leqvio® (inclisiran)
Now he owes the feds $375K
The dangers of using large language models for peer review
The dangers of using large language models for peer review The recent advances in artificial intelligence, and particularly large language models (LLM) such as chatGPT (openAI, San Francisco, CA, USA), has initiated extensive discussions in the scientific community regarding their potential uses and, more importantly,
NIH rules are supposed to stop ‘pass the harasser.’
New York hedge fund billionaire and an unnamed partner will spend $25 million relaunching research of embattled scientist
How to wrap up research projects gracefully
Four researchers offer tips on ending, redefining and handing over projects. Some research projects arrive gracefully at a natural conclusion, such as when a trainee leaves the laboratory. Others come to a screeching halt when funding runs out. Still more dance along the
Everyone Wants Your Email Address. Think Twice Before Sharing It.
Your email address has become a digital bread crumb for companies to link your activity across sites.
Why don’t identical twins have the same fingerprints? New study provides clues
Waves of chemical signals spread across developing fingers, creating one-of-a-kind patterns of ridges No two fingerprints are exactly the same. That’s what makes them so useful for police and smartphones to positively identify people. Previous research has shown genes play a role in
The developmental basis of fingerprint pattern formation and variation
Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ridges are epithelial structures that undergo a truncated hair follicle
Cancer researcher banned from federal funding for faking data in nearly 400 images in 16 grant applications
Alice C. Chang, Ph.D., Purdue University: Based on the report of an investigation conducted by Purdue University (PU) and additional analysis conducted by the Office of Research Integrity (ORI) in its oversight review, ORI found that Alice C. Chang, Ph.D. (formerly named Chun-Ju
